Current Research Interests

Michael Moore’s research interests include the toxicology of metals, risk assessment, air and water quality, alcoholism, cyanobacterial toxins and disorders of porphyrin metabolism.

Research Expertise

• Board Member Australian Pesticides and Veterinary Medicines Authority Advisory Board 2007 -
• Chair, NHMRC, Air Quality In and Around Traffic Tunnels Working Committee  2007
• Member Queensland Government Marine Stinger Advisory Committee 2007 -
• Member Australian Drug Evaluations Committee 2003 -
• Member of the National Drugs and Poisons Schedules Committee (TGA) 1999 –
• Expert advisor, Queensland EPA; Remediation of Narangba contaminated site 2006
  
• Expert Advisor - Toowoomba City Council; Waste water reuse strategy.  2006
• Queensland Health Water working Group – Environmental Health. 2006 -
• Member DVA Scientific Advisory Group Centre for Military and Veteran Health 2005
  
• Member NSW Food Authority Dioxins Expert Panel 2005 - 2007
• Member, NHMRC Working Group on Toxicity & Risk Assessment 2002 - 2005
• Chair, NHMRC Drinking Water Treatment Chemicals Working Party. 2000 - 2005
• Member External Advisory Group – Institute for Health and Environmental Studies – University of the Sunshine Coast 2003-
• Member QIMR Clinical Trial Protocol Committee – 2005 -
• Member Science Program Advisory committee University of the Sunshine Coast 2002 -
• Member of the Technical advisory committee of Environment Australia’s Air Toxics forum: 1999 - 2003
• Member Environment Australia, National Dioxins consultative Group 2001- 2006
• Expert Advisor; Stuart Facilitation Working Group, Dept of State Development.2001- 2004
• Member DHAC report on health impacts of  Indoor Air Quality, 2000
• Member Department of Veterans Affairs, Korean Veterans Mortality Study advisory committee 1998 - 2005;
• Member Department of Veterans Affairs, Korean Veterans Health Study advisory committee 2001 - 2005;
• Member Scientific Advisory committee Study of Health Outcomes in Aircraft Maintenance Personnel
  
• Member DVA expert committee; Depleted uranium Exposure and the ADF 2001-2002 
• Member of IPCS Task Groups on Lead 1993-1994;  Nitrogen Oxides 1994;  Aluminium 1995, Copper 1996, Zinc 1996, Essential Trace elements 1998 & Arsenic 1999:
• Chairman of the Community And Environmental Health Advisory Panel of the Minerals Council of Australia 1999 - 2005:
• Member: International Council on Mining & Metals Health Advisory Panel:
• Australian representative - WHO expert panel on Health effects of Dioxin exposure 1999
• Member EnHealth working party on Environmental Health Risk Assessment, 1998.
• Expert Advisor; NHMRC Dental Amalgam and mercury in dentistry working party 1998
• Member NSW ETS Standards Committee 1998
• Member Australian (NHMRC) Lead abatement evaluation steering committee 1997.
• Past Member: PACIA Community Advisory Panel 2002 - 2005
• Member Blue green Algae Task Force (Queensland) 1995-
• Member National Cyanobacterial Toxin Guidelines Working Group. 1996-. 
• Expert Advisor NHMRC working party on carcinogenic soil contaminants and the NHMRC development group on risk assessment of contaminated sites.
• Past Member Queensland Government Irukandji Task Force 2002 – 2007
• Past Member NH&MRC, Environmental Health & Nutrition Standing Committee (Toxicology Adviser)  1994–1997.
• Advisor to IPCS/ WHO; on Lead 1992 - 1994,
• Past Council member, Australasian Society for Clinical and Experimental Pharmacology and Toxicology (ASCEPT) Past Convener of the Toxicology section of ASCEPT.
• Chairman of the Local organising committee of the International Congress of Toxicology-IX,- Brisbane 2001.
• Reviewer for numerous journals; Nature, The Lancet, British Medical Journal, New Scientist, Clinical Science, Clin. Chim. Acta, Biochemical Journal, British Journal of Dermatology,  etc.

Recent Professional Experience

Michael Moore is currently Director of The National Research Centre for Environmental Toxicology. He holds the position of Professor in Medicine at the University of Queensland and Adjunct Professor of Public Health in Griffith University, Adjunct Professor in Queensland University of Technology and Adjunct Professor in the Faculty of Science, Sunshine Coast University. He is a registered Toxicologist, (Eurotox & Institute of Biology, United Kingdom), possesses a PhD in Medicine and was awarded a Doctorate in Science in the field of biochemistry in medicine and has trained in Clinical Pharmacology in the Royal Postgraduate Medical School. He is a director of the Australian Centres for Health Risk Assessment and founder member of the Australasian College of Toxicology and Risk assessment. Michael worked previously in the University of Glasgow, where he was Reader in Medicine and Therapeutics. He was a director of Monklands and Bellshill NHS Hospital Trust in Scotland and Justice of the Peace.

Academic Qualifications

• UNIVERSITY OF GLASGOW
• B.Sc., Honours, Biochemistry, 1967
• Ph.D., Medicine, 1971
• D.Sc., Biochemistry in Medicine, 1987

Professional Society Memberships

• Australasian College of Toxicology and Risk Assessment (ACTRA),
• Biochemical Society (BS),
• British Toxicological Society (BTS),
• Eurotox,
• Australasian Society of Clinical and Exprimental Pharmacologists and Toxicologists (ASCEPT)

Publications Summary

Michael has written several books and numerous book chapters and over 500 research publications.  These can be supplied if requested.

Significant publications:

1. Abu-Bakar, A., Lamsa, A., Arpiainen, A., Moore, M.R., Lang, M., and Hakkola, J. (2007). Regulation of CYP2A5 gene by the transcription factor nuclear factor (erythroid-derived 2)-like 2. Drug Metabolism and Disposition 35(5): 787-94.
2. Cooper, K.,  Noller, B.,  Connell, D.,  Yu, J.,  Sadler, R., Olszowy, H.,  Golding, G.,  Tinggi, U., Moore, M.R., and Myers, S. (2007). Public health risks from heavy metals and metalloids present in traditional Chinese medicines. J Toxicol Environ Health A. 70(19):1694-9.
3. Priestly, B.G.,  Di Marco, P., Sim, M., Moore, M.R., and Langley, A. (2007). Toxicology in Australia: A Key Component of Environmental Health. J Toxicol Environ Health A. 70(19):1578-83.
4. Krishnamohan, M., Qi, L., Lam, P.K.S., Moore, M.R., and Ng, J.C. (2007). Urinary arsenic and porphyrin profile in C57BL/6J mice chronically exposed to monomethylarsonous acid (MMA^III) for two years. Toxicol Appl Pharmacol. 2007 Jul 14; [Epub ahead of print].
5. Kimlin, M.G., Olds, W.J., and Moore, M.R. (2007). Location and Vitamin D synthesis: Is the hypothesis validated by geophysical data? J Photochem Photobiol B. 1;86(3):234-9.
6. Krishnamohan, M. Wu, H.J., Huang, S.H., Maddelena, R., Lam, P.K.S., Moore, M.R., and Ng, J.C. (2007). Urinary arsenic methylation and porphyrin profile of C57Bl/6J mice chronically exposed to sodium arsenate. Sci Total Environ. 379(2-3):235-43.
7. Haswell-Elkins, M., Imray, P., Satarug, S., Moore, M.R., and O’dea, K. (2007). Urinary excretion of cadmium among Torres Strait Islanders (Australia) at risk of elevated dietary exposure through traditional foods. J Expo Sci Environ Epidemiol. 17(4):372-7.
8. Falconer, I.R., Chapman, H.F., Moore, M.R., and Ranmuthugala, G. (2006). Endocrine-disrupting compounds: A review of their challenge to sustainable and safe water supply and water reuse. Environ Toxicol. 21(2):181-91.
9. Satarug, S., Nishijo, M., Lasker, J.M., Edwards, R.J., and  Moore, M.R. (2006). Kidney Dysfunction and Hypertension: Role for Cadmium, P450 and Heme Oxygenases? Tohoku J Exp Med. 208(3):179-202.
10. Ng, J.C., and Moore, M.R. (2005). Arsenic in drinking water: a natural killer in Bangladesh and beyond. An urgent alternative watershed management strategy is needed. Med J Aust. 183(11-12):562-3.
11. Abu-Bakar, A.,Moore, M. R., and Lang, M. A. (2005). Evidence for induced microsomal bilirubin degradation by cytochrome P450 2A5. Biochemical Pharmacology 70(10): 1527-35.
12. Baker, J.R., Edwards, R.J., Lasker, J.M., Moore, M.R., and Satarug, S. (2005). Renal and hepatic accumulation of cadmium and lead in the expression of CYP4F2 and CYP2E1. Toxicol Lett. 159(2):182-91.
13. Ng, J.C., Wang, J-P., Zheng, B., Zhai, C., Maddalena, R., Liu, F., Moore, M.R. (2005) Urinary porphyrins as biomarkers for arsenic exposure among susceptible populations in Guizhou province, China. Toxicology and Applied Pharmacology 206 176-184. 
14. Satarug, S., Nishijo, M., Ujjin, P., Vanavanitkun, Y., and Moore, M.R. (2005). Cadmium-induced nephropathy in the development of high blood pressure. Toxicol Lett. 157(1):57-68.
15. Ng J. C. and Moore M. R. (2005). Editorials: Arsenic: a natural killer in Bangladesh and beyond. Medical J. Aust. 183 (11/12): 562-3.
16. Harden, F., Mueller, J. Toms, L. Moore, M. Burniston, D. Symons, R. Ahokas, J. Fuerst, P. and Paepke. O. (2004). Determination of the levels of dioxin and dioxin-like compounds in the Australian population by analysis of pooled human breast milk. Organohalogen Compounds 66:P445: 2847-2852.
17. Abu-Bakar, A., Satarug, S., Marks, G. C., Lang, M. A., and Moore, M. R. (2004). Acute cadmium chloride administration induces hepatic and renal CYP2A5 mRNA, protein and activity in the mouse: involvement of transcription factor NRF2. Toxicology Letters 148(3): 199-210.
18. Krishnamohan, M., Wu, H., Wang, J. P., Moore, M.R. & Ng, J. C. (2004). 'Urinary porphyrin profile as an early warning biomarker in C57BL/6J mice chronically exposed to monomethylarsonous acid (MMAIII)', Toxicology and Applied Pharmacology 197(3), pp. 197 - 197.
19. Satarug, S. & Moore, M.R. (eds) (2004). Toxicology Letters 148, pp. 153 - 211.
20. Satarug, S., Nishijo, M., Ujjin, P., Vanavanitkun, Y., Baker,J.R., and Moore, M.R. (2004). Evidence for concurrent effects of exposure to environmental cadmium and lead on hepatic CYP2A6 phenotype and renal function biomarkers in nonsmokers. Environ Health Perspect.112(15):1512-8.